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| #5039729 in Books | 2011-09-29 | Original language:English | PDF # 1 | 7.10 x.90 x10.20l,2.10 | File type: PDF | 349 pages|
Proper expression, folding, transport, and clearance of proteins is critical for cell function. Chaperones and enzymes that posttranslationally assist newly synthesized proteins help ensure that they fold correctly or are degraded. Translocation machineries, proteasomes, and autophagic activities help to localize and degrade proteins as necessary. Stress and aging can cause such mechanisms to become dysfunctional or overloaded, resulting in the accumulation and aggregati...
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